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Chemical development of intracellular protein heterodimerizers
6-FAM PEG3 azide is an excellent alkyne-reactive fluorescent reagent for labeling alkyne-containing biological molecules through click chemistry
Product Name CP-DOTA Synonyms SNAP2-DOTA CAS Number Related CAS Molecular Formula C28H39ClN8O8 Molecular Weight 651
Binfunctional carboxylic acid-carboxylic acid linker
89 SMILES Cl
Mal-Acetyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE tag Chemical development of intracellular proteinSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl
