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Product Name DOTA-C2-DBCO Synonyms CAS Number 1374865-01-6 Related CAS Molecular Formula C34H42N6O8 Molecular Weight 662
Product Name Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C88H139N15O24 Molecular Weight 1791
In live HEK 293T cells
Product Name Phthalimidinoglutarimide-C3-O-PEG2-C2-amine HCl Synonyms Phthalimidinoglutarimide-4'-C3-O-PEG2-C2-amine HCl CAS Number 2138439-22-0 Related CAS Molecular Formula C22H32ClN3O6 Molecular Weight 469
Product Name MaP555-DBCO Synonyms CAS Number n/a Related CAS Molecular Formula C45H42N6O6S Molecular Weight 794
Propargyl-Acetyl-Val-Ala-PAB(m-PEG8)-Exatecan carboxylic acid Product Name DOTA-C2-DBCO Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC
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