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Mal-Propionyl-PEG2-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan AHPC COA MSDS

SKU 20561425843
4.5
USD445.00 USD481.00

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Description

COA           MSDS

It forms a covalent bond with the CLIP-tag protein

Product Name: DBCO NHS Synonyms: CAS Number: 1353016-71-3 Molecular Formula: C23H18N2O5 Molecular Weight: 402

CA-N3 is a HaloTag ligand containing an azide functional group

CA-DOTA-tris(t-Bu) can be used to attach DOTA moiety to protein

Mal-Propionyl-PEG2-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan AHPC COA MSDSSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent

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