DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Size:25mg OC(=O)C1=CC=C2C(=O)OC3(C2=C1)C1=CC(Cl)=C(O)C=C1OC1=C3C=C(Cl)C(O)=C1 Purity (HPLC): ≥ 95%

OC(=O)C1=CC=C2C(=O)OC3(C2=C1)C1=CC(Cl)=C(O)C=C1OC1=C3C=C(Cl)C(O)=C1 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

Molchanova

Product Name Pomalidomide-C2-amine HCl Synonyms Pomalidomide-4'-C2-amine HCl CAS Number 2305369-00-8 Related CAS 1957235-66-3 (free base) Molecular Formula C15H17ClN4O4 Molecular Weight 352

Product Name Thalidomide-C3-O-PEG1-C2-amine HCl Synonyms Thalidomide-4'-C3-O-PEG1-C2-amine HCl CAS Number 2138439-51-5 Related CAS Molecular Formula C20H26ClN3O6 Molecular Weight 439

Product Name Lenalidomide-5'-CO-C3-alkyne Synonyms CAS Number n/a Related CAS Molecular Formula C19H19N3O4 Molecular Weight 353

DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Size:25mg OC(=O)C1=CC=C2C(=O)OC3(C2=C1)C1=CC(Cl)=C(O)C=C1OC1=C3C=C(Cl)C(O)=C1 Purity (HPLC): ≥ 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to