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626 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
126 Purity (HPLC) >= 95% Solubility DMSO
The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate
513 SMILES OCCOCCOCCOCCOCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
It acts as a molecular glue for selective degradation of GSPT1
Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-MMAE Size:25mg 626 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(O)=O)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate
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