DBCO-Lys(m-PEG4)-Val-Cit-PAB Size:50mg 351 SMILES OCCOCC#CC1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1 Purity (HPLC)

351 SMILES OCCOCC#CC1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

NCCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin

Product Name Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C75H102FN11O24 Molecular Weight 1560

Product Name Methyl 3-[3-(methoxy-d3)phenyl]propanoate Synonyms CAS Number n/a Related CAS Molecular Formula C11H14O3 Molecular Weight 197

DBCO-Lys(m-PEG4)-Val-Cit-PAB Size:50mg 351 SMILES OCCOCC#CC1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,