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demonstrating a DC50 of 19 nM against GFP-HaloTag7 fusion proteins
CA-PEG4-Azide can be used to attach azide moiety to protein
It’s a bifunctional molecule featuring a chloroalkane group (specific for HaloTag) and an O6-benzylguanine (BG) derivative (specific for SNAP-tag)
generating a strong fluorescent signal
308 SMILES OCCC#CC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:5mg demonstrating a DC50 of 19SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage
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