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DOTA-PEG5-C2-amine piperazine NRX-1532 acts as molecular glue

SKU 77327164612
4.6
USD145.00 USD188.00

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Description

NRX-1532 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta-catenin by the 26S proteasome

71 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCBr)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name CA-Oregon Green Synonyms Oregon Green-Halo

Product Name MaP555 NHS Synonyms CAS Number N/A Related CAS Molecular Formula C31H31N5O8S Molecular Weight 633

Product Name Thalidomide-O-acetamido-PEG6-C2-acid Synonyms Thalidomide-4'-O-acetamido-PEG6-C2-acid CAS Number n/a Related CAS Molecular Formula C30H41N3O14 Molecular Weight 667

DOTA-PEG5-C2-amine piperazine NRX-1532 acts as molecular glueDOTA bifucational chelator containing an amine group, a PEG linker, and the macrocyclic chelator DOTA ( 1,4,7,10 tetraazacyclododecane 1,4,7,10 tetraacetic acid). It can be used in many different diagnostic and therapeutic applications, such as MRI contrast agents, PET and SPECT imaging agents, and radiotherapeutic agents. Product Name DOTA PEG5 C2 amine Synonyms CAS Number n a Related CAS Molecular Formula C28H54N6O12 Molecular Weight 666. 77 SMILES

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