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Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:25mg 36 SMILES Cl

SKU 84346816066
4.8
USD495.00 USD524.00

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Description

36 SMILES Cl

The primary aliphatic amine of the red-fluorescentSulforhodamine 101 cadaverine (Texas Red C)can be reversibly coupled to aldehydes and ketones to form a Schiff base - which can be reduced to a stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3) to form new biotinylated probes

Product Name: 6-TAMRA Synonyms: 6-Carboxytetramethylrhodamine CAS Number: 91809-67-5 Molecular Formula: C25H22N2O5 Molecular Weight: 430

Product Name CA-Oregon Green Synonyms Oregon Green-Halo

and the commercial tetramethylrhodamine maleimides and iodoacetamides often have lower purities than other tetramethylrhodamine labeling reagents (such as TAMRA SE reagents) due to their synthetic difficulties

Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:25mg 36 SMILES ClSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization,

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